December 27, 2007
The authors set out to conduct a systematic review and critical appraisal of the economic evaluations of one-to-one interventions to reduce STDs and teenage pregnancy.
Four electronic bibliographic databases from 1990 to January 2006 were searched using keywords including: teenage, pregnancy, adolescent, unplanned, unwanted, cost benefit, cost utility, economic evaluation, cost effectiveness and all terms for STDs, including specific disease names. Studies were included that assessed a wide range of one-to-one interventions aimed at reducing STDs. Outcomes included major outcomes averted, life years and quality-adjusted life years (QALY). All studies were assessed against quality criteria.
The researchers identified 3,190 papers, of which 55 were included. Most studies found one-to-one interventions were either cost-saving or cost-effective. One, however, highlighted the need to target the population to receive post-exposure prophylaxis to reduce HIV transmission. Most of the studies employed a static approach that does not consider the potential re-infection of treated patients.
Sexually Transmitted Infections
10.01.2007; Vol. 83; No. 6: P. 441-446; L. Barham; D. Lewis; N. Latimer