Top 10 Research Reports of 2004

Table of Contents

• Introduction
• AIDS Epidemic Update: December 2004, UNAIDS/WHO
• Lopinavir/Ritonavir Monotherapy in Treatment-Naive Patients
• Atazanavir -- The Little PI That Could
• A5095 and the Triple-Nucleoside Saga
• The Risk of NNRTI Resistance Following Perinatal Nevirapine and Ramifications for Subsequent Antiretroviral Therapy Success
• The Genomics of Efavirenz Toxicity
• Stable Viral Load but Evolving Drug Resistance
• How Stable Is Stable Low-Level Viremia?
• The Down Low
• HCV Therapy in Coinfected Patients
• Summary
• References

Introduction

For over 25 years the deadliest infectious disease epidemic in history has raged across this planet. During these 2.5 decades, advances in our ability to respond to the HIV epidemic have come in fits and starts. The last 10 years, in particular, have witnessed a virtual renaissance in HIV research and care that has allowed us to consider HIV infection a manageable, even chronic, disease.

More recently, however, we have reached a plateau, with major clinical breakthroughs becoming rarer and less dramatic. For example, in 2004 no major developments in HIV care were announced nor were any new antiretrovirals approved. However, there were a number of significant contributions that helped refine our understanding of how to use the HIV therapies we have at hand. Some of these developments have already reached the clinic and have led to improvements in HIV therapeutics, while the full effects of others have yet to be realized.

...

Want to read the rest of this article? To learn more about our audience, we're asking readers to register in order to receive full access to all of our materials. Please click here to begin your quick, free registration at The Body PRO.

If you're already registered with The Body PRO, please log in:

E-mail Address
Password
	Remember my login

Forgot your password?