March 12, 2003
Thirty patients -- 15 coinfected with HIV and HCV, and 15 age-matched patients with HCV alone -- took high-dose IFN-alpha-2a therapy for 24 weeks. The report states that HIV viral loads dropped from roughly 7,410 copies/mL to 320 copies/mL after two weeks. Data showed that HCV RNA was undetectable in four of 12 evaluable HIV-positive patients, and in six of 15 HCV-alone patients after 24 weeks. Three HIV-positive patients had to discontinue treatment because of IFN-related toxicity.
"Induction therapy and the dose of IFN should be evaluated in combination therapy with IFN and ribavirin," Hanabusa concluded. The full report, "Efficacy of Induction Therapy with High-Dose Interferon for Patients with Hemophilia and Human Immunodeficiency Virus-Hepatitis C Coinfection," was published in Clinical Infectious Diseases (2002;35(12):1527-1533).
01.24.03; Michael Greer
The content on this page is free of advertiser influence and was produced by our editorial team. See our content and advertising policies.
|This Week in HIV Research: New Discovery in How HIV Hijacks a Cell|
|Research in New York Confirms That MSM Will Likely Follow Up After a Positive at-Home HIV Test|
|This Week in HIV Research: Viral Suppression Without Treatment in Monkeys|
|This Week in HIV Research: A New Glimpse Into HAND|
|This Week in HIV Research: Injectable PrEP Shows Promise in New Study|
|New York Study Finds Almost Half of HIV-Positive Gay Men Co-Infected With Hepatitis C Have Detectable Levels of Hepatitis C Virus in Their Rectal Fluid|