June 15, 2004
Researchers from The Johns Hopkins Children's Center found that with careful planning and adherence to treatment plans, these HIV-positive patients can stay healthy. A new study, presented at the annual Pediatric Academic Societies' meeting in San Francisco, reported successful treatment of six HIV-positive children using tailored genotype-linked testing and a Web-based algorithm tool to assist in medication decisions.
"If HIV patients develop a drug resistance, the results could possibly be life-threatening, since resistance reduces the chance a new drug regimen will be successful," said the study's lead author, Nancy Hutton, MD, director of the Intensive Primary Care Clinic at the Children's Center.
"However, these findings show it is possible to create an effective salvage therapy using such technological tools as genotype testing in conjunction with Web-based algorithms to find the most appropriate treatment for each individual patient, as long as the treatments are initiated in a controlled setting to ensure that every single dose is given every single time and to monitor and control side effects if they occur," Hutton added.