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AIDS 2004; Bangkok, Thailand; July 11-16, 2004

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UNBP0708 06/14

The Body PRO Covers: The XV International AIDS Conference

Non-Hodgkin's Lymphoma Rates Lower in HAART-Treated Patients

July 12, 2004

Background

Untreated HIV infection confers a huge increase in the incidence of non-Hodgkin's lymphoma (NHL). Understanding the extent to which HAART mitigates this risk is of vital importance to HIV-infected persons.

Details of This Study

Waterson et al report on a 9,621-person cohort assembled at London's Chelsea & Westminister Hospital. Over the entire span of the cohort's observation, 280 patients were diagnosed with lymphoma (206 with systemic NHL, 55 with primary cerebral lymphoma, and 19 with Hodgkin's lymphoma). During the 1996-2003 interval, 102 of 5,832 persons were diagnosed with lymphoma. Multivariate analysis found decreased age, higher nadir CD4+ and CD8+ counts and exposure to HAART to be associated with lower NHL incidence rates.


Non-Hodgkin's Lymphoma Rates Lower in HAART-Treated Patients


Significance for Patients/Clinicians

This study provides a good basis for the very encouraging belief that today's HAART regimens will be protective against NHL.

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Reference

Abstract: Anti-Retroviral Treatment Regimens and the Prevention of Systemic HIV-Related Non-Hodgkin's Lymphoma (Poster MoPeB3257)
Authored by: A Waterston, J Stebbing, C Thirlwell, T Newson-Davis, S Mandalia, M Nelson, B G Gazzard, M Bower


This article was provided by TheBodyPRO.com. It is a part of the publication The XV International AIDS Conference.
 



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