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TheBodyPRO.com Covers CROI 2017

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HIV Clinical Trials Must Enroll More Women

March 6, 2017

People who are designing the studies, who are funding the studies, need to make [enrolling women] a priority.

-- Rena Patel, M.D.

In an interview on behalf of IFARA at CROI 2017, Andy Kaytes spoke with Rena Patel, M.D., and Monica Gandhi, M.D., about HIV in women. Studies have shown that women taking certain forms of hormonal contraceptives have a higher risk of acquiring HIV than those who do not use such pregnancy prevention.

Pregnancy presents a unique opportunity to identify and reach women who may benefit from oral pre-exposure prophylaxis. Studies have not shown adverse birth outcomes for women who took tenofovir disproxil fumarate (TDF, Viread)) during pregnancy.

A newer form of this drug, tenofovir alafenamide (TAF, Vemlidy), may accumulate at lower levels in vaginal tissue than in rectal tissue. Yet, the current clinical trial comparing TDF and TAF has not enrolled any cisgender women. To understand the biological and social differences that contribute to divergent responses to HIV prevention and treatment in women and men, enrolling women in clinical investigations must become a priority.

Watch the video to learn more:



About the panelists:

  • Andy Kaytes, moderator.
  • Rena Patel, M.D., University of Washington, Seattle.
  • Monica Gandhi, M.D., M.P.H., University of California, San Francisco Center for AIDS Research.

The video above has been posted on TheBodyPRO.com with permission from our partners at the International Foundation for Alternative Research in AIDS (IFARA). Visit IFARA's website or YouTube channel to watch more video interviews from the conference, as well as earlier meetings.

Barbara Jungwirth is a freelance writer and translator based in New York.

Follow Barbara on Twitter: @reliabletran.


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This article was provided by TheBodyPRO.com. It is a part of the publication The 24th Conference on Retroviruses and Opportunistic Infections.
 


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Please note: Knowledge about HIV changes rapidly. Note the date of this summary's publication, and before treating patients or employing any therapies described in these materials, verify all information independently. If you are a patient, please consult a doctor or other medical professional before acting on any of the information presented in this summary. For a complete listing of our most recent conference coverage, click here.

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