Spotlight Center on HIV Prevention Today


How Frequently Should People Be Tested for HIV?

February 6, 2017

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HIV testing is the gateway to HIV diagnosis and engagement in treatment, care and support for people living with HIV. It is also the gateway to enhanced engagement in HIV prevention, care and support for people who test HIV negative but are at ongoing high risk of transmission.

One factor for service providers to consider when delivering or discussing testing is how often a client should be tested for HIV. This article summarizes the results from a systematic review examining testing frequency recommendations in Canadian and international HIV testing guidelines.1

Why Is the Frequency of HIV Testing Important?

In Canada we are not doing well at diagnosing HIV and engaging people in treatment and care. According to recently revised 2014 estimates from the Public Health Agency of Canada (PHAC), about 13,000 of the 65,040 people living with HIV in Canada are unaware of their HIV status.2 This represents about 20% of all people with HIV.

The importance of testing for HIV so that people are aware of their HIV infection as early as possible cannot be overstated, particularly given recent advances in our understanding of HIV treatment. Advances in treatment mean that people with HIV can live almost as long and as healthily as people who are uninfected.3 But to get the most out of treatment, however, research shows it needs to be started soon after someone is infected with the virus.4 Research also now tells us that the consistent and correct use of antiretroviral treatment (ART) by people living with HIV to maintain an undetectable viral load is a highly effective strategy to reduce the risk of the sexual transmission of HIV.5,6,7,8,9,10,11,12,13


What Kind of Research Does the Systematic Review Include?

The systematic review sought to identify HIV testing frequency recommendations for different populations by reviewing HIV testing guidelines developed in Canada and internationally.1

HIV testing guidelines support and standardize testing and are based on research and practice from the field. They may also take into consideration the local experience of HIV if the guidelines are informing services in a particular region. In addition to HIV testing frequency, guidelines can include recommendations on who to test, when to offer testing, pre- and post-test counselling, and legal and ethical issues such as consent and confidentiality.

The review was based on 34 guidelines. A guideline was included if it:

  • Provided direction on how often HIV testing should occur. The direction could be in the form of a position, recommendation or guidance and could address testing for one or more specific population or the general population.
  • Was available in English or French.
  • Was published from January 2000 to August 2015.

Characteristics of the guidelines included:

  • The guidelines came from Canada, Africa, Asia, Australia, Europe, the United States and the World Health Organization. Sixty-five percent of the guidelines came from the United States or Europe.
  • The guidelines were developed by government health departments and organizations and by expert groups such as associations of health professionals.
  • The populations most commonly addressed were pregnant women, MSM and the general population.

Canadian guidelines included in the review were:

What HIV Testing Frequencies Did the Guidelines Recommend?

The review compared testing frequency recommendations by examining how often a given recommendation was made. The recommendations for pregnant women, MSM and the general population, the three groups most often addressed by the guidelines, were summarized individually. Common recommendations in other populations were also noted.

Pregnant women

Recommendations for pregnant women were found in 20 guidelines and included:

  • Screening for HIV as early as possible during pregnancy (nine guidelines) such as at the first prenatal appointment (four guidelines)
  • Routine testing (three guidelines)
  • Re-testing in the third trimester regardless of the women's HIV risk (four guidelines) or repeat testing if the women's risk of infection is high (three guidelines)

Men who have sex with men

Recommendations for men who have sex with men were found in 19 guidelines and included:

  • Testing at least annually (14 guidelines)
  • Routine testing with no specific interval given (three guidelines)
  • More frequent testing with no specific interval given due to insufficient evidence to inform a recommendation (two guidelines)

General population

Recommendations for the general population were found in 14 guidelines and included:

  • Routine or normalized testing with no specific interval given (eight guidelines)
  • A specific time interval such as every five years (two guidelines)

Four guidelines also noted there was insufficient evidence to inform a recommendation for a specific time interval for the general population.

Other populations

Testing at least once a year was a common recommendation and was the most frequent recommendation for:

  • People who use injection drugs (11 of 13 guidelines that mentioned this population)
  • People with HIV-positive partners (six of seven guidelines)
  • People with multiple sex partners (four of seven guidelines)
  • Sex workers and their clients (four of four guidelines)
  • Migrant people from HIV-endemic countries (three of four guidelines)
  • Indigenous people (two of three guidelines)
  • People with a partner of unknown status (two of two guidelines)

Recommendations for people who have been diagnosed with another sexually transmitted infection (STI) included routine testing (three guidelines) and re-testing after each new STI diagnosis (two guidelines).

Other populations mentioned in four or fewer guidelines included adolescents, prisoners and trans men and women. Recommendations for these populations were more varied, and included testing at least annually, routine testing and risk-based screening.

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This article was provided by Canadian AIDS Treatment Information Exchange. It is a part of the publication Prevention in Focus: Spotlight on Programming and Research. Visit CATIE's Web site to find out more about their activities, publications and services.

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