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CROI 2015: University of California Researchers Discuss Neurological Issues in HIV (Video)

April 7, 2015

Fred Schaich of IFARA spoke with Josué Pérez-Santiago, Ph.D., and Sara Gianella, M.D., of the Center for AIDS Research at the University of California, San Diego, about neurological issues in HIV. Both researchers work on understanding better when and how the body's barrier between the blood and the brain is breached, in particular with regard to HIV infection. Gianella specializes in HIV pathogenesis and the question of whether HIV can maintain reservoirs of the virus in the brain. If so, drugs must be developed that can cross the blood-brain barrier to effectively target HIV in every compartment of the body.

Pérez-Santiago emphasized the importance of HIV prevention, because "even with successful therapy the body is never close to what it was before infection." He focuses on determining how systemic inflammation in the cerebrospinal fluid may be the result of gut bacteria helping the virus to breach the brain-blood barrier. The neurological problems associated with HIV may be a result of such a breach.

Watch the video to learn more:

About the panelists:

  • Josué Pérez-Santiago, Ph.D., Center for AIDS Research, UCSD, San Diego, California
  • Sara Gianella, M.D., Center for AIDS Research, UCSD, San Diego, California

The video above has been posted on with permission from our partners at the International Foundation for Alternative Research in AIDS (IFARA). Visit IFARA's website or YouTube channel to watch more video interviews from the conference, as well as earlier meetings.

Barbara Jungwirth is a freelance writer and translator based in New York.

Follow Barbara on Twitter: @reliabletran.

Copyright © 2015 Remedy Health Media, LLC. All rights reserved.

This article was provided by TheBodyPRO. It is a part of the publication The 22nd Conference on Retroviruses and Opportunistic Infections (CROI 2015).

Reader Comments:

Comment by: Gloria Irizarry (Bronx, New York) Wed., May. 6, 2015 at 1:09 am UTC
I saw the video about the peer support. Where can I find a peer support in the area I live in. I am HIV positive from a blood transfusion. I use to go to support groups as a child but as I got older the groups had stopped or people just stopped going. I would like to start going to groups again.
Reply to this comment

Comment by: Dr Billy Levin (South Africa) Tue., Apr. 14, 2015 at 7:13 pm UTC
about 7% of our population have ADHD .Among HIV+ children the figure is 28% for a very obvious reason I have published on this subject to "right to Care" if you are interested.
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