CROI 2015: University of California Researchers Discuss Neurological Issues in HIV (Video)
April 7, 2015
Fred Schaich of IFARA spoke with Josué Pérez-Santiago, Ph.D., and Sara Gianella, M.D., of the Center for AIDS Research at the University of California, San Diego, about neurological issues in HIV. Both researchers work on understanding better when and how the body's barrier between the blood and the brain is breached, in particular with regard to HIV infection. Gianella specializes in HIV pathogenesis and the question of whether HIV can maintain reservoirs of the virus in the brain. If so, drugs must be developed that can cross the blood-brain barrier to effectively target HIV in every compartment of the body.
Pérez-Santiago emphasized the importance of HIV prevention, because "even with successful therapy the body is never close to what it was before infection." He focuses on determining how systemic inflammation in the cerebrospinal fluid may be the result of gut bacteria helping the virus to breach the brain-blood barrier. The neurological problems associated with HIV may be a result of such a breach.
Watch the video to learn more:
Barbara Jungwirth is a freelance writer and translator based in New York.
Follow Barbara on Twitter: @reliabletran.
Copyright © 2015 Remedy Health Media, LLC. All rights reserved.
This article was provided by TheBodyPRO. It is a part of the publication The 22nd Conference on Retroviruses and Opportunistic Infections (CROI 2015).
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