February 7, 2014
The HCV Treatment Cascade
Between the significant liabilities of traditional therapy and the significant shortfalls of common monitoring techniques, it is perhaps unsurprising that clinical rates of HCV treatment success in HIV-coinfected patients are often miserably low. Cox pointed to a 2006 study of 845 patients receiving regular HIV care via the Johns Hopkins HIV clinic around the turn of the century -- a study that found only 6 of the 845 actually achieved a sustained virologic response on HCV therapy.
What makes these numbers particularly alarming is that they may not even be an extreme example. "Those data come from a clinic where people are more than a little in tune to the need to treat hepatitis C," Cox said. "It's probably worse in other clinics."
Cox added that the challenges of real-world HCV treatment success are not unique to the HIV-coinfected population. "In a VA [U.S. Department of Veterans Affairs] study of about 100,000 patients with hep C, regardless of HIV or not, only about 2 and half percent were cured of their hepatitis C," she said.
Myles Helfand is the editorial director of TheBody.com and TheBodyPRO.com.
Follow Myles on Twitter: @MylesatTheBody.
The content on this page is free of advertiser influence and was produced by our editorial team. See our content and advertising policies.
|PrEP Prescriptions Rise Sharply, but Unequally, in New York City|
|How to Reverse Implicit Bias in HIV Care: 6 Steps to Take Today|
|A Review of Late-Stage HIV Antiretroviral Candidates at IDWeek 2017|
|Free Your (and Carl's) Mind: An Open Letter to Anthony Fauci About HIV Prevention Research Priorities|
|This Week in HIV Research: Injectable PrEP Shows Promise in New Study|
|Let's Advance the Conversation Among Black Women on HIV and PrEP|