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Differences Between HIV-Infected Men and Women in Antiretroviral Therapy Outcomes -- Six African Countries, 2004-2012

November 29, 2013

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TABLE 3. Percentage of Antiretroviral Therapy (ART) Enrollees Alive and on Therapy, by Years After ART Initiation, and Attrition* Rate and Risk for Attrition, by Sex -- Retrospective Cohort Studies, Six African Countries

Years after ART
initiation

Côte d'Ivoire

Swaziland

Mozambique

Women
%

Men
%

 

Women
%

Men
%

 

Women

%

Men

%

 

0.5

81

75

 

86

81

 

84

81

 

1

76

70

 

82

77

 

78

73

 

1.5

72

66

 

79

74

 

74

69

 

2

67

60

 

76

71

 

71

66

 

2.5

63

55

 

74

68

 

69

64

 

3

59

51

 

71

64

 

68

59

 

3.5

56

48

 

71

63

 

65

53

 

4

51

43

 

68

62

 

65

52

 

4.5

47

40

 

65

62

 

62

52

 

Attrition rate

Per 100 person-
years

(95% CI)

 

Per 100 person-
years

(95% CI)

 

Per 100 person-
years

(95% CI)

 

Sex

         

Men

24.7

(22.4-27.2)

 

16.2

(14.4-18.2)

 

23.0

(19.8-26.9)

 

Women

18.7

(17.4-20.2)

 

12.4

(11.3-13.6)

 

17.9

(15.7-20.4)

 

Unadjusted risk for attrition

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

Sex

         

Men

Referent

--

 

Referent

--

 

Referent

--

 

Women

0.78

(0.70-0.86)

<0.001

0.78

(0.68-0.90)

0.002

0.79

(0.71-0.88)

<0.001

Adjusted risk for attrition

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

Sex

         

Men

Referent

--

 

Referent

--

 

Referent

--

 

Women

0.74

(0.65-0.83)

<0.001

0.85

(0.74-0.97)

0.021

0.79

(0.70-0.89)

<0.001


TABLE 3. (Continued) Percentage of Antiretroviral Therapy (ART) Enrollees Alive and on Therapy, by Years After ART Initiation, and Attrition Rate and Risk for Attrition, by Sex -- Retrospective Cohort Studies, Six African Countries

Years after ART
initiation

Zambia

Uganda

Tanzania

Women

%

Men

%

 

Women

%

Men

%

 

Women

%

Men

%

 

0.5

81

75

 

94

91

 

76

75

 

1

77

69

 

90

88

 

71

67

 

1.5

73

65

 

87

84

 

65

62

 

2

70

60

 

85

81

 

62

59

 

2.5

66

57

 

82

78

 

58

57

 

3

63

54

 

78

76

 

57

55

 

3.5

61

51

 

77

74

 

52

52

 

4

57

49

 

75

73

 

49

50

 

4.5

55

47

 

73

71

 

48

44

 

Attrition rate

Per 100 person-
years

(95% CI)

 

Per 100 person-
years

(95% CI)

 

Per 100 person-
years

(95% CI)

 

Sex

         

Men

22.9

(20.3-25.9)

 

9.9

(8.2-11.9)

 

25.5

(22.2-29.2)

 

Women

16.2

(14.5-18.1)

 

7.9

(6.8-9.1)

 

24.0

(21.7-26.6)

 

Unadjusted risk for attrition

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

Sex

         

Men

Referent

--

 

Referent

--

 

Referent

--

 

Women

0.73

(0.62-0.86)

<0.001

0.82

(0.65-1.03)

0.091

0.93

(0.78-1.10)

0.406

Adjusted risk for attrition

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

HR

(95% CI)

p-
value

Sex

         

Men

Referent

--

 

Referent

--

 

Referent

--

 

Women

0.82

(0.65-1.02)

0.079

0.88

(0.66-1.18)

0.407

0.89

(0.71-1.12)

0.311

Abbreviations: CI = confidence interval; HR = hazard ratio.

* From death, stopping ART, or loss to follow-up.

† Multivariate analysis included only complete cases: Côte d'Ivoire (2,394), Swaziland (2,090), Mozambique (1,426), Zambia (972), Uganda (1,056), and Tanzania (938). In addition to sex, multivariate analysis adjusted for the following characteristics at ART initiation: age, CD4 count, World Health Organization HIV disease stage, and treatment regimen.

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This article was provided by U.S. Centers for Disease Control and Prevention. It is a part of the publication Morbidity and Mortality Weekly Report. Visit the CDC's website to find out more about their activities, publications and services.
 

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