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Weighing Risks of TDF/FTC PrEP Side Effects in People Without HIV

Winter 2012

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References

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    17A. "Among those who discontinued tenofovir use, the time period following cessation was not significantly associated with either higher or lower risks of proteinuria (HR=1.05 per year, 95% CI: 0.93-1.18, p = 0.41) or rapid decline (HR=1.05 per year, 95% CI: 0.94-1.16, p=0.42), although there was a marginal association of time off tenofovir with [chronic kidney disease] (HR=1.22 per year, 95% CI: 0.99-1.50, p=0.055). All hazard ratios remained greater than unity, which suggests that the effects of tenofovir on kidney disease risk were not reversible following discontinuation."
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This article was provided by The Center for AIDS. It is a part of the publication Research Initiative/Treatment Action!. Visit CFA's website to find out more about their activities and publications.
 

 

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