HIV Conferences: A Look Back at 2012

Shaking the Status Quo: 2012 HIV/AIDS Conference Research Highlights

November 15, 2012


crossed fingers

The Search for a Cure

For years, Timothy Brown -- the "Berlin patient" -- had been the lone individual in existence who could justifiably claim to have been cured of his HIV infection. This summer, he may have been joined by two others.

At the XIX International AIDS Conference, Daniel Kuritzkes, M.D., presented a study outlining how two HIV-infected men showed no traces of the virus in their blood more than two years after receiving an autologous stem cell transplant.

The procedure differed from the one Brown received in a pivotal way: While Brown's donor cells lacked the CCR5 receptor, the primary means by which HIV attaches to CD4+ cells, the two men received donor cells that did have the CCR5 receptor and were fully susceptible to HIV. If there were no need to find a CCR5-deficient matching donor for the transplant to be successful, it would make such a procedure far more realistic.

In addition, unlike Brown, the two men remained on antiretroviral therapy during the transplant period, which is believed to be key to their immune system's ability to completely suppress viral replication.

"The importance of our findings is that we have evidence now that we can protect uninfected cells from becoming infected when they're transplanted into an HIV-infected patient, a form of PrEP at the cellular level, if you will," Kuritzkes said.

These findings arguably made the loudest noise in the cure subfield this year, but they are by no means the only movement on the cure research front. Research continues in many directions as the world waits for further proof that latent HIV reservoirs can be activated and eliminated once and for all.

This article was provided by TheBodyPRO.com.

Reader Comments:

Comment by: Adam (bUAbBcbGM) Wed., Jan. 9, 2013 at 10:39 am EST
It's a pleasure to find someone who can iedntify the issues so clearly
Reply to this comment

Comment by: Solikhul (QkvGZTuGMZoZYmFF) Wed., Jan. 9, 2013 at 10:38 am EST
yes it does, thank you!! I have been experimenting with my 2-strand twsits lately. I sweat a lot in my scalp, so after about 6-7 days I can't take it anymore. I have to wash. I did do a co-wash while the twsits were still in. It came out very nice, and got me though another 3-4 days before I had to completely do a shampoo wash. Thank you so much for your very helpful videos and positive sweet spirit. God Bless!
Reply to this comment

Comment by: Pratik (EbAYdcFtT) Wed., Jan. 9, 2013 at 10:37 am EST
Candida is a type of fungus that grows in your body. It's mcpioscoirc so you don't see it. When too much of it gets in your digestive system, you get permanent rotten breath. Go to any health food store and ask for medicine to do a candida cleanse, and you'll get it. The price is reasonable (anywhere from $10-$40) considering you won't need to buy anywhere near as much gum or tic-tacs for the rest of your life. I used to buy a huge box of tic-tacs to last only two weeks! It was hell.
Reply to this comment

Comment by: Gurbachan S (Ottawa) Wed., Nov. 28, 2012 at 1:39 pm EST
A great summary of the conference and where everything stands as at today.

I think 30 years is too long. I blame part of this on the parochial interest of Corporations and Institutes. If there was high level collaboration this problem could have been easily resolved.

After two years of treatment the laboratory details of the Berlin Man and the other two are still very scanty and not in the public domain.

We need to give hope to the 30 million infected world0wide that we are doing our best.

Best regards
Reply to this comment

Add Your Comment:
(Please note: Your name and comment will be public, and may even show up in
Internet search results. Be careful when providing personal information! Before
adding your comment, please read TheBody.com's Comment Policy.)

Your Name:

Your Location:

(ex: San Francisco, CA)

Your Comment:

Characters remaining: