Simplifying HAART Regimen Fails to Maintain HIV-1 Viral Suppression
October 23, 2012
A pilot study by Harold P. Katner, M.D., of Mercer University School of Medicine in Macon, Ga., and colleagues assessed the durability of HIV-1 virologic suppression in persons who changed from a lopinavir/ritonavir-based triple highly active antiretroviral therapy (HAART) regimen once or twice a day to lopinavir/ritonavir monotherapy once daily. This was an observational cohort study to determine the proportion of subjects who sustained virologic suppression through the 48th week following their switch to the daily lopinavir/ritonavir monotherapy. Researchers presented the study at IDWeek 2012, a joint meeting of the Infectious Diseases Society of America (IDSA), the Society for Health and Epidemiology of America (SHEA), the HIV Medicine Association (HIVMA), and the Pediatric Infectious Diseases Society (PIDS).
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