How Will We Finally Create a Successful Vaccine for HIV?


Myron Cohen, Director, Infectious Diseases at UNC-Chapel Hill

Myron Cohen

Director, Infectious Diseases at UNC-Chapel Hill

I think the biggest challenge is scientific, unequivocally. The challenge is which road to pursue. Which of the things that are increasingly visible to us -- neutralizing antibodies and antibody-dependent cell-mediated cytotoxicity (ADCC) -- have a greater probability of being successful in preventing HIV with urgency?

The second issue is clinical trial design. You have to really think hard about the clinical trial design. If we make a vaccine designed to induce the response that we think is most likely to protect humans, how do we get the credible answer as fast as possible? And while we're doing that, we really need to understand surrogates of immunity. If you start injecting people with a vaccine, and you fail to see the surrogates of immunity on which it's based, you might want to have that as one of the considerations.

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Reader Comments:

Comment by: Dheeraj (kmYlrEJszythLwlInXL) Wed., Jan. 9, 2013 at 3:17 pm UTC
I would try a galvanic spa, works the best for me and pelpoe I know. My niece had pimples on her nose. One use and they were gone the next day. We saw almost immediate results. A little bit pricey, but you can use it for a long, long time.
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Comment by: Alireza (rNbOfbWWcvVIeQWFYRD) Wed., Jan. 9, 2013 at 10:53 am UTC
No extra charge to all medcial claims, so you will not find that claim to reduce high blood pressure But there are many that help support healthy blood pressure. There are Fish Oil, Hawthorn, L-arginine (helps circulation), garlic, Bonito Peptides, Coleus Forskohlii and C12 peptides. Good luck!
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Comment by: Woojong (tYRJhNUGM) Wed., Jan. 9, 2013 at 9:27 am UTC
these are weird answers below try Neutrogena Grapefruit Acne Wash .I recmnmeod it .it helps emerge other breakouts blackheads or just to cleanse your skin get rid of pimples.if you don't want to spend 7-10 dollars , then just make lemonade , not that much sugar , drink lemonade alot , it helps shed dead skin . then make sure to clean the pimple TWICE a day .or put a ice cube over it to reduce redness .. theres really no way to get rid of it instantly with a home remedy . try these , if all else fails try the wash up above.
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Comment by: Samuel Margolies (USA) Wed., Nov. 14, 2012 at 11:58 pm UTC
Ultimately HIV will be controlled and cured when the virus can be tricked. What this means rather than a direct attack is for the researchers to determine. When a cure is found, this insight will be found sound. Use it.
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Comment by: Kyle N. (Barrie, ON) Fri., Oct. 12, 2012 at 4:29 pm UTC
Thank you for this article. I personally found it very informing on the obstacles that people in this field have to face when developing an HIV vaccine, or any vaccine for that matter.
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