August 3, 2011
Half of the hepatitis C virus (HCV)-infected participants in a small midstage trial receiving a four-drug combination that included two Vertex Pharmaceuticals medications were able to discontinue treatment after 12 weeks, the company reported.
According to Vertex, 400 milligrams of its experimental oral drug VX-222 (a polymerase inhibitor) was administered with its recently approved Incivek (a protease inhibitor) and the standard regimen of pegylated interferon and ribavirin. The trial, known as Zenith, also revealed that 12 weeks after the combo discontinuation, 93 percent of those patients retained undetectable HCV levels.
Those patients not eligible to stop treatment at 12 weeks received another 12 weeks of standard therapy. All 13 who continued in the trial appeared cured at 24 weeks, Vertex said.
The content on this page is free of advertiser influence and was produced by our editorial team. See our content and advertising policies.
|CROI 2017 Preview: New Research on HIV Cure and Treatment|
|No Evidence of Accelerated Brain Aging in HIV-Positive People on Effective ART|
|Final HIV Research Highlights From CROI 2017|
|Research Shows 47% Reduction in STIs Among Gay Men Who Took Doxycycline After Sex|
|What to Expect for CROI 2017|
|Don't Get Left Behind: New Scientific Findings to Be Presented at CROI 2017|