June 21, 2011
The increasing incidence of oropharyngeal cancers in the United States since 1984 is associated with human papillomavirus, according to research presented recently at the 2011 American Society of Clinical Oncology Annual Meeting in Chicago.
HPV prevalence in 271 oropharyngeal cancer cases, documented in population-based registries, grew significantly during the study period (1984-2004), the researchers found. Compared to HPV-negative cases, median survival was greater for HPV-positive cases and grew significantly over time. This was not true for HPV-negative cases, however.
Population-level incidence of HPV-positive oropharyngeal cancers grew 225 percent during 1988-2004 (0.8/100,000 to 2.6/100,000). If the trend were to continue, HPV-positive cases would double from 4,000-4,500 in 2004 to 8,500 by 2020, researchers reported, with the increase occurring mainly in men.
06.01.2011; Lara Salahi
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