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HIV Care Today


More on Low (but Detectable) Viral Loads -- Is Knowing This Useful?
By Paul Sax, M.D.
February 3, 2012

I have a very smart, very experienced colleague -- clue, his initials are CC, and he doesn't pitch for the Yankees -- who continues to use bDNA testing for HIV viral load monitoring. You know, the assay with a lower limit of detection of 75 copies. He knows that bDNA is less sensitive than PCR. He knows that it's more expensive than PCR.

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Avoiding the Slippery Slope to Burnout
By David Fawcett, Ph.D., L.C.S.W.
January 30, 2012

The text alert came in the middle of a session. It was from a colleague and read simply "call asap." I dialed his number between patients, and when he answered, I was surprised at his quiet tone and his admission that he was really shaken. We often utilized each other for consultation and support, but on this day he sounded defeated. He told me that a patient had just died.

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Generic Lamivudine Has Arrived
By Paul Sax, M.D.
January 22, 2012

An e-mail from a patient last week: "Just got refills. Epivir is now generic??? Refill is simply labeled Lamivudine Tablets by Aurobindo Pharma USA, Inc ... but made in India. Should I be concerned about that???"

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Journal Club: In Early HIV Infection, Little Reason to Delay Therapy
By Paul E. Sax, M.D.
January 8, 2012

Over in Journal of Infectious Diseases, the so-called Setpoint study -- a randomized strategy trial -- investigated whether a 36-week period of treatment would delay the need to go on continuous HIV therapy, compared with observation. After 130 of a planned 150 patients were enrolled, a Data Safety Monitoring Board elected to stop the study due to this key finding: "... the higher rate of progression to needing treatment in the Deferred Treatment group (50%) versus the Immediate Treatment (10%) group."

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No HIV in Pepsi? Now THAT'S a Relief
By Paul E. Sax, M.D.
December 14, 2011

How reassuring to be treated with the following news: "An SMS has been circulating that Pepsi products are contaminated with HIV but Permanis Sandilands Sdn Bhd has clarified that this is a hoax. Its marketing vice-president Hemalatha Ragavan said there was no truth to it. She urged people not to believe such claims." I have a couple of thoughts about this breaking story.

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A Bad Note in HIV Prevention: Our VOICE May Be Hoarse, but the Opera Isn't Over
By Bethsheba Johnson, G.N.P.-B.C., A.A.H.I.V.S.
November 29, 2011

Another disappointing note was bellowed out this month concerning the discontinuation of part of a significant HIV prevention trial in women. The 1% tenofovir (Viread) gel arm of the VOICE phase 2B clinical trial was halted early by the independent Data and Safety Monitoring Board (DSMB).

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Under The Radar: Mental Health and HIV Risk
By David Fawcett, Ph.D., L.C.S.W.
November 22, 2011

Getting the level of new infections down to zero will require breakthroughs not only in medications and improved interventions, but also a broadening of our understanding about the underlying causes of high-risk behaviors which can increase vulnerability for HIV, specifically, mental health concerns.

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Who Should Care for the Aging HIV Patient? Everything Old Is ... Oh You Know
By Paul E. Sax, M.D.
November 21, 2011

Over in Journal Watch AIDS Clinical Care, Carlos Del Rio reviews a couple of remarkable studies on HIV and aging.

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Testosterone Replacement Therapy and Polycythemia in HIV-Infected Patients
By Nelson Vergel, B.S.Ch.E., M.B.A.
November 16, 2011

A research letter recently published in the journal AIDS by Vorkas et al determined that testosterone use was associated with polycythemia, and intramuscular administration demonstrated a stronger association than topical (testosterone patch) use. No adverse cardiovascular or thrombotic events were observed. HIV-infected patients taking testosterone should undergo routine hematologic monitoring with adjustment of therapy when appropriate.

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HCV Treatment Studies at AASLD: Wow ... and I Mean WOW!
By Paul E. Sax, M.D.
November 10, 2011

I didn't attend "The Liver Meeting" (the nickname for the annual meeting of the American Association for the Study of Liver Diseases, AASLD), but the studies presented there this week on HCV treatment were absolutely mind-boggling.

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This article was provided by TheBodyPRO.com.
 

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