As part of the usual flurry of studies released just before major scientific meetings, results of two pre-exposure prophylaxis (PrEP) trials in heterosexual men and women have just been made public:
The result of the above stellar behavior? I would do virtually anything to try and help her. Back in the late 1990s, when she was very sick with AIDS, one of my fellows said it best: "There's just something about her that makes you want to take care of her." Exactly.
It was the peak time for the cherry blossoms in Washington, D.C. -- or so I was told. I only caught a glimpse of them from the Metro as I was riding in from Reagan National, and a few times out the window of the hotel conference room (along with rain and even a brief burst of hail during that tempestuous spring weekend). But I wasn't in town for sightseeing: I was one of about 15 individuals from around the country selected to participate in the Training of Trainers program, a component of the National Association of Social Workers' HIV/AIDS Spectrum: Mental Health Training and Education of Social Workers Project.
A while back, after a challenging day in the office, I came home to the pleasure of reading the Winter 2011 edition of HIV Specialist, the magazine of the American Academy of HIV Medicine (AAHIVM). Of particular interest to my weary brain was an article by Bruce J. Packett II entitled "The Evolution of Viral Load Technologies."
Of the HIV medications in development with potential activity against highly resistant HIV (i.e., patients with GSS=0), two may become available within the next year: ibalizumab (formerly TNX-355), a monoclonal antibody currently under development by TaiMed Biologics, and dolutegravir (formerly GSK1349572), a second-generation integrase inhibitor made by ViiV Healthcare).
The studies on abacavir and its potential association with increased cardiovascular risk have been inconsistent ever since the news first broke at CROI 2008. But recently the data have been swirling around so fast and furious that it seems appropriate to take out this famous Greek epithet.
Every spring, on the white, sandy beaches of the Florida Panhandle, an unlikely gathering takes place. On that narrow strip of land, between the Gulf of Mexico and Choctawhatchee Bay, 450 HIV-positive men and women from around the country, but mostly from the Southeast, come together amidst occasional spring breakers for a weekend of socializing, education, some silliness, a few tears, and just plain fun.
In the recent post on the approval of generic Combivir -- and the lack of availability of generic Epivir (lamivudine, 3TC), which was both anticipated and likely to be more useful -- I speculated there were several possible causes of this surprising turn of events.
If your patient population is anything like mine, then you see a lot of active drug users. My dear friend, Suzanne Carlberg-Racich, Ph.D., M.S.P.H., reminded me of my faux pas immediately after the article was published. I'd like to share the ensuing conversation with you, because it includes some very good tips.
Periodically I like to give an informal quiz to the medical students about HIV epidemiology. It's a multiple choice question that goes something like this: