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AZT and lipoatrophy/lipodystrophy Posted: Aug 27, 2007 QUESTION: How significant is lipoatroph/ lipodystrophy associated with AZT because in our resource limited region we substitute d4T with AZT when this happens?


RESPONSE FROM: While fat wasting during AZT treatment is well documented this seems to happen more rarely and at a slower pace than that seen with d4T. I think in your situation, changing from d4T to AZT when fat wasting is noticed makes sense. Tenofovir and abacavir, when they become more widely available, will be even better alternatives. DW

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