Ask Your Colleagues About:

Treatment Strategies
  

Truncal Obesity/Lipodsytrophy

Posted: Mar 2, 2006

QUESTION:

Has there been any research conducted on abating or mitigating truncal obesity/lipodystrophy after discontinuing anti-retroviral therapydrugs that precipitate this condition?


  

RESPONSE FROM:   

    Well, for one thing I am still a bit unclear which medicine cause truncal obseity so which to discontinue is a problem. Although the popular belief is that PIs cause this, studies have not been consistent in supporting this impression.

    Recent data from the Retro conference suggests that in men with lowish testosterone levels, supplemental testosterone can reduce subcutaneous adipose tissue but does not improve visceral fat. In patients with glucose intolerance, metformin has decreased abdominal girth (and weight) but side effects can be a problem.

    Check out the Bodypro.com coverage of CROI 2006 for a review of body shape studies presented at the conference.

    DW




Terms of Use: Please remember that this forum is designed for educational purposes only, and experts are not engaged through this forum in rendering legal or medical advice or professional services. Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Questions and messages posted to this forum are not statements of advice, opinion, or information of The Body PRO, Body Health Resources Corporation or any sponsor of this forum.

Visitors submitting questions remain solely responsible for the content of their messages. Information provided by experts is general only and should not be used for diagnosing or treating a health problem or a disease, or relied upon as legal or other professional advice. This information is not a substitute for professional advice or care.

powered by ExpertViewpoint

global Toolbox