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Viread/Coviracil Posted: Dec 5, 2002 QUESTION: I saw the big news from Gilead that they will be taking over the development of coviracil. How long do you think it will take for a combined version of viread/coviracil to be approved? Do you see this as a good fit? Dr. Phillips


RESPONSE FROM: Dear Dr. Phillips- thank you for your question. The proposed acquisition of Triangle by Gilead certainly raises some very interesting questions. Clearly an area of interest is the development of a fixed dose formulation of coviracil (FTC) and tenofovir. Since both drugs can be potentially administered once daily, this would be a very attractive once-daily combination. The development of such a FDC drug would take some time, perhaps a couple of years-- requiring a significant number of studies of bioequivalence and chemical stability. Of course, this all hinges on the approval of FTC too. -BY

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