PC pneumonitis
Posted: Aug 25, 2007
QUESTION:
male 46 years, positive since 1990, in triple antiretroviral scheme, hospitalized 3 months ago with neumonitis by PNCarinni. Got treatment with trimetoprim and sulfamtx for 2 months, now asymthomatic for 1 month. Total lymphocites 1183, CD19 154, CD4 in 308, CD3 899, CD8 592.NK 130. Esphyrometry 95% O2. We dont have reactive for viral load at the hosp right now. How long do you recomend to continue profilaxis with bactrim in low doses? Thanks for your help
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RESPONSE FROM: 
Thank you for your post.
We typically treat pneumocystic pneumonia for 3 weeks, using trimethoprim/sulfamethoxazole (Bactrim, Septra, Cotrimoxazole). Secondary prophylaxis with single strength TMP/SMX daily or double strength 3-times weekly is continued until the CD4 count is reproducibly above 200 (15%).
Good luck with your patient, BY
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