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PIs - inducers or inhibitors of CYP3A4

Posted: Sep 17, 2006

QUESTION:

I was recently looking at the prescribing information for Lexiva, and noticed that it states amprenavir to be both an inhibitor and inducer of CYP3A4. I cannot find any published data to support this - how is this possible?


  

RESPONSE FROM:   

    I think you need a better search engine (check Pubmed)..

    Here's a recent publication on the P450 interactions of fosamprenavir (Lexiva, Telzir).

    BY




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