Kaletra & Epivir
Posted: Jun 24, 2006
QUESTION:
Dr Young,
My concern is that I've never heard of the regimen that my doctor prescribed 3 years ago. I'm taking only Kaletra & Epivir with excellent results. Being diagnosed positive in 1991, my viral load is <50 and t-cells at >700 and 27%. I've built resistance to most other drugs, including Zerit & AZT. Sustiva is intolerable for me. Truly, I live an excellent quality of life with absolutely no side effects or symptoms. Do you agree with this regimen or have suggestions? THANKS
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RESPONSE FROM: 
Thanks for your post.
While your regimen is unconventional, there are several data points that are in your favor. First off, your viral load has been undetectable; hence, it seems like your regimen is certainly potent enough for your virus. Second, there are several studies that have looked at using lopinavir/ritonavir (or other boosted PIs) as PI-alone treatment-- all with quite impressive results. Also, I should point out that I'd be reluctant to endorse once-daily lopinavir/ritonavir in your situation, given the risk of lower drug levels.
So, overall, if your doctor feels that you have limited other options (one might consider the use of tenofovir with 3TC or FTC in your case), your tolerating your regimen well and have no problems with your viral load, I'd forge onward.
Best of health to you. BY
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