Ah, the holy grail of HIV treatments.
The major issue are several; relating to the rate of mutations (and risk of resistance) and mostly to the simple fact that HIV, like all retroviruses, is able to integrate it's genetic material into the human chromosome. Once there, the viral genetic material can lie dormant for as long as the infected cell lives.
Unfortunately, we estimate that some HIV infected cells can live for many decades.
We'll need novel ways to activate such latently infected cells; more potent and resistance-avoiding drugs before we'll see an effective eradication strategy. BY
