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HIV and anesthetic management

Posted: Jun 11, 2006

QUESTION:

Hello, I'm working as anesthethist at a little spanish hospital in Madrid; till now we don't have any experience in anesthesia of HIV patient; we don't know whether to stop HIV treatment before surgery and how many days before surgery; what to do whith the HIV treatment if pateints are not able to drink more days after the surgery. Whether general anesthesia or neuroaxial anesthesia are better for this patients. Whether epidural complications have been seen in this patients. Is there any web with a perioperative protocol of patients with HIV? Thank you


  

RESPONSE FROM:   

    Gracias for your post.

    In general, patients with HIV can be managed like HIV- patients, with regard to surgery. Indeed, there is at least one large study from the KP group in California that showed that HIV+ patients did not have any significant increase in perioperative complications (including epidural ones). Following this, the considerations of general versus regional anesthesia are those that apply to the general population.

    There are two areas of difference among HIV+s worth noting-- the first is anesthesia management; generally this is not a major area of concern, except for the potential for drug-drug interactions among patients receiving HIV protease inhibitors, especially ritonavir. In these cases a consultation with a pharmacologist prior to anesthesia would be worth while.

    Secondly, the issue of having a patient not take anything by mouth (NPO status) can sometimes restrict the intake of HIV medications. If this is only for a 12 hour period, skipping a single or couple of doses can be done without need for treatment or managment modification (though I'd make sure to let the prescribing HIV healthcare provider know; in advance if possible). Longer discontinuations of medications may require some advance planning, particularly if the patient's regimen includes a non-nucleoside inhibitor. Because of significant differences in the half-lives of the nucleosides and non-nucleosides, many experts will recommend discontinuation of the nucleosides for upwards of 7 days prior to a planned discontinuation of non-nucleosides.

    Deseo que este es de beneficidad. Nos escribe si hay otras preguntas. BY




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